Center for Molecular Innovation and Drug Discovery

Design. Create. Innovate.

SYNTHETIC & MEDICINAL CHEMISTRY INSTRUMENTATION

Our collection of state-of-the-art research instrumentation is designed to carry out our mission of providing chemistry services for drug discovery and chemical biology researchers. Contact the ChemCore team at [email protected] for questions and additional information on our collection.

Agilent high-throughput mass spectrometry-directed analytical to preparative LC purification system
Mass-directed analytical-to-preparative (A2Prep) system for the analysis and purification of samples.
Agilent 1260 analytical HPLC with UV and ELS detection
 Used for the analysis of samples and fractions.
Agilent 1200 Preparative HPLC
Enables reversed-phase high performance liquid chromatography of samples and crude mixtures.
Genevac HT4 Centrifugal Evaporator
A centrifugal vacuum evaporator capable of high performance on a variety of solvents.
VirTis AdVantage Plus BenchTop Freeze Dryer
 A shelf lyophilizer capable of drying a large number of samples at once; compatible with non-standard vessels.
Biotage Isolera Flash Purification System
Enables high performance flash chromatography of mixtures and samples.
 ThalesNano H-Cube hydrogenation system
Capable of continuous-flow hydrogenation reactions.
 Biotage microwave reactor
Enables microwave-assisted organic synthesis.
 Forma 8690 -80 °C Freezer
Used to store final compounds at low temperatures.
 Acquity UPLC H-Class System
Enables LC/MS analysis of reaction mixtures, samples, and final compounds.
 Gilson Preparative HPLC System with GX-27L liquid handler
Enables reversed-phase high performance liquid chromatography of samples and crude mixtures.
 Genevac EZ-2 Plus centrifugal evaporator
A centrifugal vacuum evaporator capable of high performance on a variety of solvents.
In addition to this instrumentation, we also use the following software: eLN (electronic lab notebook), CDD (Collaborative Drug Discovery data management system), and TriposBenchware 3D Explorer Visualization Software (molecular modeling and computational chemistry software).
For instrumentation used by our Cheminformatics Specialist, click here.